Sandy Springs Back Pain Related to Inflammation Reduced with Melatonin

Inflammation. Disc Degeneration. There is a connection. Inflammation acts as the body’s response system to harmful stimuli (injury, pathogens, metabolic stress – a disc herniation compressing a nerve!) as it attempts to restore itself to normal before the harm was achieved. Cross Chiropractic Center is always amazed at what the body can do! Cross Chiropractic Center sees its Sandy Springs chiropractic care as a partner of the body’s system in healing especially when there is spine pain. Chiropractic care uses many tools like spinal manipulation, exercise, and nutrition to take care of the body. Melatonin is one nutritional tool that is proving value by interrupting the inflammatory process related disc herniation that brings about pain relief: back, neck, spine-related.

DISC DEGENERATION AND INFLAMMATION AND 'AUTOPHAGY'

Inflammatory markers interleukin-1β (IL-1β), interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) are related to intervertebral disc degeneration. (1) IL-1 β actually promotes itself, its own expression, by upregulating NLRP3 inflammasome activation. (2) The body regulates itself down to the cellular level via autophagy, the natural process via which the body’s cells clean out damaged (ie, by inflammation) or unneeded parts. In a recent study, melatonin boosted autophagy and lessened the degradation of the disc’s extracellular matrix (technically marked by a decrease in marker LC3B, autophagasomes and autolysosomes and inhibition of the NF-kB signaling pathway). The end conclusion was that melatonin inhibits intervertebral disc degeneration by promoting autophagy. (3) Wow. Cross Chiropractic Center is encouraged by this research to see just how well melatonin can work for Sandy Springs back pain linked to disc degeneration.

MELATONIN AND ITS HEALING WAYS FOR THE DISC

Disc degeneration is such a common condition seen at Cross Chiropractic Center that positive news of melatonin’s benefits are quite rousing. A new study explained how melatonin could modulate the extracellular matrix of the disc remodeling process started by IL-1 β. Further, melatonin decreased the inflammatory cell collection and decreased the release of linked inflammatory markers IL-1β, IL-6, and TNF-α. With this new finding that melatonin interrupted the IL-1B feedback loop, researchers proposed that melatonin may contribute to the restoration process of intervertebral discs after damage was already present. (1) Cross Chiropractic Center continues following the new research on the role inflammation plays in Sandy Springs disc degeneration and melatonin’s role in combatting it.

INFLAMMATION AND MELATONIN

The significance of melatonin in assisting to slow or stop painful conditions due to inflammation is rising. The description of melatonin as a multitasking molecule influencing mood, immunity, and energy among other things is quite fitting. It’s also anti-oxidant, anti-aging, and anti-inflammatory, specifically by blocking the activation of inflammasomes (4) Melatonin’s formal chemical name is as about as long as its list of tasks: N-acetyl-5-methoxytryptamine. The pineal gland secretes melatonin naturally. Melatonin impacts the body’s aging, anti-inflammatory, anti-apoptosis (cell death), and autophagy (cell-cleanout) activities. (1) Melatonin’s specific influence on inflammation and disc degeneration is most interesting to Cross Chiropractic Center and our Sandy Springs back pain patients.

CONTACT Cross Chiropractic Center

Listen to this PODCAST with Dr. Hrefna Sylvia based in Iceland where back pain isn’t much different from any other country on The Back Doctors Podcast with Dr. Michael Johnson as she describes how The Cox® Technic System of Spinal Pain Management addresses disc degeneration for relief of chronic low back pain in her patient.

Schedule your Sandy Springs chiropractic appointment with Cross Chiropractic Center today. We can talk about the role inflammation plays in your back pain experience and how melatonin may help with the related disc degeneration.

 
Cross Chiropractic Center presents new findings that melatonin interrupts the inflammatory process in disc degeneration that causes back pain. 
 
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"This information and website content is not intended to diagnose, guarantee results, or recommend specific treatment or activity. It is designed to educate and inform only. Please consult your physician for a thorough examination leading to a diagnosis and well-planned treatment strategy. See more details on the DISCLAIMER page. Content is reviewed by Dr. James M. Cox I."